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CRISPR-Guided Proximity Labeling of RNA–Protein Interactions

Proximity labeling employs modified biotin ligases or peroxidases that produce reactive radicals to covalently label proximate proteins with biotin in living cells. The resulting biotinylated proteins can then be isolated and identified. A combination of programmable DNA targeting and proximity labe...

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Detalles Bibliográficos
Autores principales: Lu, Mingxing, Wang, Zuowei, Wang, Yixiu, Ren, Bingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498842/
https://www.ncbi.nlm.nih.gov/pubmed/36140717
http://dx.doi.org/10.3390/genes13091549