Pan-cancer gene expression analysis of tissue microarray using EdgeSeq oncology biomarker panel and a cross-comparison with HER2 and HER3 immunohistochemical analysis

Molecular and protein biomarker profiling are key to oncology drug development. Antibody-drug conjugates (ADCs) directly deliver chemotherapeutic agents into tumor cells based on unique cancer cell biomarkers. A pan-cancer tissue microarray (TMA) data set and gene panel were validated and gene signa...

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Detalles Bibliográficos
Autores principales: Inaki, Koichiro, Shibutani, Tomoko, Maeda, Naoyuki, Eppenberger-Castori, Serenella, Nicolet, Stefan, Kaneda, Yuki, Koyama, Kumiko, Qiu, Yang, Wakita, Kenichi, Murakami, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498941/
https://www.ncbi.nlm.nih.gov/pubmed/36137139
http://dx.doi.org/10.1371/journal.pone.0274140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498941/
https://www.ncbi.nlm.nih.gov/pubmed/36137139
http://dx.doi.org/10.1371/journal.pone.0274140

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