Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice

TRPV4 channel activation in endothelial cells leads to vasodilation, while impairment of TRPV4 activity is implicated in vascular dysfunction. Strategies that increase TRPV4 activity could enhance vasodilation and ameliorate vascular disorders. Here, we show that supplementation with eicosapentaenoi...

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Detalles Bibliográficos
Autores principales: Caires, Rebeca, Garrud, Tessa A.C., Romero, Luis O., Fernández-Peña, Carlos, Vásquez, Valeria, Jaggar, Jonathan H., Cordero-Morales, Julio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498980/
https://www.ncbi.nlm.nih.gov/pubmed/36070688
http://dx.doi.org/10.1016/j.celrep.2022.111306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498980/
https://www.ncbi.nlm.nih.gov/pubmed/36070688
http://dx.doi.org/10.1016/j.celrep.2022.111306

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