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Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice
TRPV4 channel activation in endothelial cells leads to vasodilation, while impairment of TRPV4 activity is implicated in vascular dysfunction. Strategies that increase TRPV4 activity could enhance vasodilation and ameliorate vascular disorders. Here, we show that supplementation with eicosapentaenoi...
Autores principales: | Caires, Rebeca, Garrud, Tessa A.C., Romero, Luis O., Fernández-Peña, Carlos, Vásquez, Valeria, Jaggar, Jonathan H., Cordero-Morales, Julio F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498980/ https://www.ncbi.nlm.nih.gov/pubmed/36070688 http://dx.doi.org/10.1016/j.celrep.2022.111306 |
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