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Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells via Modulation of the Akt/MAPK/AP-1 Pathway

Inhibition of inflammatory responses from the spike glycoprotein of SARS-CoV-2 (Spike) by targeting NLRP3 inflammasome has recently been developed as an alternative form of supportive therapy besides the traditional anti-viral approaches. Clerodendrum petasites S. Moore (C. petasites) is a Thai trad...

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Detalles Bibliográficos
Autores principales: Arjsri, Punnida, Srisawad, Kamonwan, Mapoung, Sariya, Semmarath, Warathit, Thippraphan, Pilaiporn, Umsumarng, Sonthaya, Yodkeeree, Supachai, Dejkriengkraikul, Pornngarm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498987/
https://www.ncbi.nlm.nih.gov/pubmed/36142258
http://dx.doi.org/10.3390/ijms231810346