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Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts

Subepithelial human esophageal myofibroblasts (HEMFs) in gastroesophageal reflux disease (GERD) are exposed to luminal contents via impaired squamous epithelium barrier integrity. The supernatant of HEMFs treated with acidic bile salts reflective of in vivo reflux increases squamous epithelial thick...

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Detalles Bibliográficos
Autores principales: Patankar, Madhura, Li, Meng, Khalatbari, Atousa, Castle, Joshua D., Hu, Liping, Zhang, Chunying, Shaker, Anisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498994/
https://www.ncbi.nlm.nih.gov/pubmed/36142285
http://dx.doi.org/10.3390/ijms231810371