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TAMC: A deep-learning approach to predict motif-centric transcriptional factor binding activity based on ATAC-seq profile

Determining transcriptional factor binding sites (TFBSs) is critical for understanding the molecular mechanisms regulating gene expression in different biological conditions. Biological assays designed to directly mapping TFBSs require large sample size and intensive resources. As an alternative, AT...

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Detalles Bibliográficos
Autores principales: Yang, Tianqi, Henao, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499209/
https://www.ncbi.nlm.nih.gov/pubmed/36094959
http://dx.doi.org/10.1371/journal.pcbi.1009921