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The Relative Abundances of Human Leukocyte Antigen-E, α-Galactosidase A and α-Gal Antigenic Determinants Are Biased by Trichostatin A-Dependent Epigenetic Transformation of Triple-Transgenic Pig-Derived Dermal Fibroblast Cells

The present study sought to establish the mitotically stable adult cutaneous fibroblast cell (ACFC) lines stemming from hFUT2×hGLA×HLA-E triple-transgenic pigs followed by trichostatin A (TSA)-assisted epigenetically modulating the reprogrammability of the transgenes permanently incorporated into th...

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Detalles Bibliográficos
Autores principales: Samiec, Marcin, Wiater, Jerzy, Wartalski, Kamil, Skrzyszowska, Maria, Trzcińska, Monika, Lipiński, Daniel, Jura, Jacek, Smorąg, Zdzisław, Słomski, Ryszard, Duda, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499218/
https://www.ncbi.nlm.nih.gov/pubmed/36142211
http://dx.doi.org/10.3390/ijms231810296