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The Relative Abundances of Human Leukocyte Antigen-E, α-Galactosidase A and α-Gal Antigenic Determinants Are Biased by Trichostatin A-Dependent Epigenetic Transformation of Triple-Transgenic Pig-Derived Dermal Fibroblast Cells
The present study sought to establish the mitotically stable adult cutaneous fibroblast cell (ACFC) lines stemming from hFUT2×hGLA×HLA-E triple-transgenic pigs followed by trichostatin A (TSA)-assisted epigenetically modulating the reprogrammability of the transgenes permanently incorporated into th...
Autores principales: | Samiec, Marcin, Wiater, Jerzy, Wartalski, Kamil, Skrzyszowska, Maria, Trzcińska, Monika, Lipiński, Daniel, Jura, Jacek, Smorąg, Zdzisław, Słomski, Ryszard, Duda, Małgorzata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499218/ https://www.ncbi.nlm.nih.gov/pubmed/36142211 http://dx.doi.org/10.3390/ijms231810296 |
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