Recent Advances in PROTACs for Drug Targeted Protein Research

Proteolysis-targeting chimera (PROTAC) is a heterobifunctional molecule. Typically, PROTAC consists of two terminals which are the ligand of the protein of interest (POI) and the specific ligand of E3 ubiquitin ligase, respectively, via a suitable linker. PROTAC degradation of the target protein is...

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Detalles Bibliográficos
Autores principales: Yao, Tingting, Xiao, Heng, Wang, Hong, Xu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499226/
https://www.ncbi.nlm.nih.gov/pubmed/36142231
http://dx.doi.org/10.3390/ijms231810328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499226/
https://www.ncbi.nlm.nih.gov/pubmed/36142231
http://dx.doi.org/10.3390/ijms231810328

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