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Recent Advances in PROTACs for Drug Targeted Protein Research
Proteolysis-targeting chimera (PROTAC) is a heterobifunctional molecule. Typically, PROTAC consists of two terminals which are the ligand of the protein of interest (POI) and the specific ligand of E3 ubiquitin ligase, respectively, via a suitable linker. PROTAC degradation of the target protein is...
Autores principales: | Yao, Tingting, Xiao, Heng, Wang, Hong, Xu, Xiaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499226/ https://www.ncbi.nlm.nih.gov/pubmed/36142231 http://dx.doi.org/10.3390/ijms231810328 |
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