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Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma

Nrf2 (nuclear factor E2-related factor 2, encoded by Nfe2l2) acts as a master transcriptional regulator in mediating antioxidant, detoxification, and cytoprotective responses against oxidative, electrophilic, and metabolic stress, but also plays a crucial role in cancer metabolism and multiple oncog...

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Detalles Bibliográficos
Autores principales: Chen, Feilong, Xiao, Mei, Feng, Jing, Wufur, Reziyamu, Liu, Keli, Hu, Shaofan, Zhang, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499251/
https://www.ncbi.nlm.nih.gov/pubmed/36142252
http://dx.doi.org/10.3390/ijms231810342