The Asparaginyl Endopeptidase Legumain: An Emerging Therapeutic Target and Potential Biomarker for Alzheimer’s Disease

Alzheimer’s disease (AD) is incurable dementia closely associated with aging. Most cases of AD are sporadic, and very few are inherited; the pathogenesis of sporadic AD is complex and remains to be elucidated. The asparaginyl endopeptidase (AEP) or legumain is the only recognized cysteine protease t...

Descripción completa

Detalles Bibliográficos
Autor principal: Song, Mingke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499314/
https://www.ncbi.nlm.nih.gov/pubmed/36142134
http://dx.doi.org/10.3390/ijms231810223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499314/
https://www.ncbi.nlm.nih.gov/pubmed/36142134
http://dx.doi.org/10.3390/ijms231810223

Ejemplares similares