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Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1

Platelet and coagulation activation are highly reciprocal processes driven by multi-molecular interactions. Activated platelets secrete several coagulation factors and expose phosphatidylserine, which supports the activation of coagulation factor proteins. On the other hand, the coagulation cascade...

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Detalles Bibliográficos
Autores principales: De Simone, Ilaria, Baaten, Constance C. F. M. J., Jandrot-Perrus, Martine, Gibbins, Jonathan M., ten Cate, Hugo, Heemskerk, Johan W. M., Jones, Chris I., van der Meijden, Paola E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499330/
https://www.ncbi.nlm.nih.gov/pubmed/36142125
http://dx.doi.org/10.3390/ijms231810203