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The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency

Background: Hereditary angioedema (HAE) is a rare, genetic disease caused by the decreased level or function of the C1 inhibitor. The primary mediator of symptoms in HAE is bradykinin acting through its two receptors, namely receptors 1 (BR1) and 2 (BR2). Although BR2 is well characterized, the role...

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Detalles Bibliográficos
Autores principales: Dyga, Wojciech, Obtulowicz, Aleksander, Mikolajczyk, Tomasz, Bogdali, Anna, Dubiela, Pawel, Obtulowicz, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499460/
https://www.ncbi.nlm.nih.gov/pubmed/36142237
http://dx.doi.org/10.3390/ijms231810332