Microglial CD74 Expression Is Regulated by TGFβ Signaling

SIMPLE SUMMARY: In the present study, we provided evidence that TGFβ signaling regulated the expression of the microglia activation marker CD74. Our data demonstrated that TGFβ1 inhibited LPS-induced upregulation of CD74. Moreover, inhibition of microglial TGFβ signaling in vitro and silencing of TG...

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Detalles Bibliográficos
Autores principales: Jahn, Jannik, Bollensdorf, Antonia, Kalischer, Christopher, Piecha, Robin, Weiß-Müller, Jana, Potru, Phani Sankar, Ruß, Tamara, Spittau, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499470/
https://www.ncbi.nlm.nih.gov/pubmed/36142162
http://dx.doi.org/10.3390/ijms231810247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499470/
https://www.ncbi.nlm.nih.gov/pubmed/36142162
http://dx.doi.org/10.3390/ijms231810247

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