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Microglial CD74 Expression Is Regulated by TGFβ Signaling
SIMPLE SUMMARY: In the present study, we provided evidence that TGFβ signaling regulated the expression of the microglia activation marker CD74. Our data demonstrated that TGFβ1 inhibited LPS-induced upregulation of CD74. Moreover, inhibition of microglial TGFβ signaling in vitro and silencing of TG...
Autores principales: | Jahn, Jannik, Bollensdorf, Antonia, Kalischer, Christopher, Piecha, Robin, Weiß-Müller, Jana, Potru, Phani Sankar, Ruß, Tamara, Spittau, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499470/ https://www.ncbi.nlm.nih.gov/pubmed/36142162 http://dx.doi.org/10.3390/ijms231810247 |
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