The Inflammasome Activity of NLRP3 Is Independent of NEK7 in HEK293 Cells Co-Expressing ASC

The cytosolic immune receptor NLRP3 (nucleotide-binding domain, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3) oligomerizes into the core of a supramolecular complex termed inflammasome in response to microbes and danger signals. It is thought that NLRP3 has to bind NEK7 (NI...

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Detalles Bibliográficos
Autores principales: Machtens, Dominik Alexander, Bresch, Ian Philipp, Eberhage, Jan, Reubold, Thomas Frank, Eschenburg, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499477/
https://www.ncbi.nlm.nih.gov/pubmed/36142182
http://dx.doi.org/10.3390/ijms231810269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499477/
https://www.ncbi.nlm.nih.gov/pubmed/36142182
http://dx.doi.org/10.3390/ijms231810269

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