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TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model

The blood-brain barrier (BBB) is a selective barrier and a functional gatekeeper for the central nervous system (CNS), essential for maintaining brain homeostasis. The BBB is composed of specialized brain endothelial cells (BECs) lining the brain capillaries. The tight junctions formed by BECs regul...

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Detalles Bibliográficos
Autores principales: Versele, Romain, Sevin, Emmanuel, Gosselet, Fabien, Fenart, Laurence, Candela, Pietra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499506/
https://www.ncbi.nlm.nih.gov/pubmed/36142143
http://dx.doi.org/10.3390/ijms231810235