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Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion

Muscle cell fusion is a multistep process where the final step of the reaction drives progression beyond early hemifusion events to complete fusion. This step requires activity of the muscle-specific fusogen Myomerger, a single-pass transmembrane protein containing 84 amino acids with an ectodomain...

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Detalles Bibliográficos
Autores principales: Gamage, Dilani G., Melikov, Kamran, Munoz-Tello, Paola, Wherley, Tanner J., Focke, Leah C., Leikina, Evgenia, Huffman, Elliana, Diao, Jiajie, Kojetin, Douglas J., Prasad, Vikram, Chernomordik, Leonid V., Millay, Douglas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499509/
https://www.ncbi.nlm.nih.gov/pubmed/36095199
http://dx.doi.org/10.1073/pnas.2202490119