Cargando…
Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion
Muscle cell fusion is a multistep process where the final step of the reaction drives progression beyond early hemifusion events to complete fusion. This step requires activity of the muscle-specific fusogen Myomerger, a single-pass transmembrane protein containing 84 amino acids with an ectodomain...
Autores principales: | Gamage, Dilani G., Melikov, Kamran, Munoz-Tello, Paola, Wherley, Tanner J., Focke, Leah C., Leikina, Evgenia, Huffman, Elliana, Diao, Jiajie, Kojetin, Douglas J., Prasad, Vikram, Chernomordik, Leonid V., Millay, Douglas P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499509/ https://www.ncbi.nlm.nih.gov/pubmed/36095199 http://dx.doi.org/10.1073/pnas.2202490119 |
Ejemplares similares
-
Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm
por: Golani, Gonen, et al.
Publicado: (2021) -
Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
por: Quinn, Malgorzata E., et al.
Publicado: (2017) -
Expression of Myomaker and Myomerger in myofibers causes muscle pathology
por: Witcher, Phillip C., et al.
Publicado: (2023) -
Extracellular annexins and dynamin are important for sequential steps in myoblast fusion
por: Leikina, Evgenia, et al.
Publicado: (2013) -
IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger
por: Kurosaka, Mitsutoshi, et al.
Publicado: (2023)