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Implanted synthetic cells trigger tissue angiogenesis through de novo production of recombinant growth factors

Progress in bottom-up synthetic biology has stimulated the development of synthetic cells (SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing diseased natural cells and addressing medical needs. Here, we report that SCs genetically encoded to produce proangiogenic...

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Detalles Bibliográficos
Autores principales: Chen, Gal, Levin, Rotem, Landau, Shira, Kaduri, Maya, Adir, Omer, Ianovici, Iris, Krinsky, Nitzan, Doppelt-Flikshtain, Ofri, Shklover, Jeny, Shainsky-Roitman, Janna, Levenberg, Shulamit, Schroeder, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499519/
https://www.ncbi.nlm.nih.gov/pubmed/36095208
http://dx.doi.org/10.1073/pnas.2207525119