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A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
The neocortex, the center for higher brain function, first emerged in mammals and has become massively expanded and folded in humans, constituting almost half the volume of the human brain. Primary microcephaly, a developmental disorder in which the brain is smaller than normal at birth, results mai...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499540/ https://www.ncbi.nlm.nih.gov/pubmed/36095192 http://dx.doi.org/10.1073/pnas.2206147119 |