A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

The neocortex, the center for higher brain function, first emerged in mammals and has become massively expanded and folded in humans, constituting almost half the volume of the human brain. Primary microcephaly, a developmental disorder in which the brain is smaller than normal at birth, results mai...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lei, Park, Jun Young, Liu, Fengming, Olesen, Kris M., Hou, Shirui, Peng, Jamy C., Infield, Jordan, Levesque, Anna C., Wang, Yong-Dong, Jin, Hongjian, Fan, Yiping, Connelly, Patrick J., Pruett-Miller, Shondra M., Hu, Miaofen G., Hinds, Philip W., Han, Young-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499540/
https://www.ncbi.nlm.nih.gov/pubmed/36095192
http://dx.doi.org/10.1073/pnas.2206147119

Ejemplares similares

Ejemplares similares