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Ait1 regulates TORC1 signaling and localization in budding yeast

The target of rapamycin complex I (TORC1) regulates cell growth and metabolism in eukaryotes. Previous studies have shown that nitrogen and amino acid signals activate TORC1 via the highly conserved small GTPases, Gtr1/2 (RagA/C in humans), and the GTPase activating complex SEAC/GATOR. However, it r...

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Detalles Bibliográficos
Autores principales: Wallace, Ryan L, Lu, Eric, Luo, Xiangxia, Capaldi, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499541/
https://www.ncbi.nlm.nih.gov/pubmed/36047762
http://dx.doi.org/10.7554/eLife.68773