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Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion

Synchronous release at neuronal synapses is accomplished by a machinery that senses calcium influx and fuses the synaptic vesicle and plasma membranes to release neurotransmitters. Previous studies suggested the calcium sensor synaptotagmin (Syt) is a facilitator of vesicle docking and both a facili...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, McDargh, Zachary A., Li, Feng, Krishnakumar, Shyam S., Rothman, James E., O’Shaughnessy, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499556/
https://www.ncbi.nlm.nih.gov/pubmed/36103579
http://dx.doi.org/10.1073/pnas.2208337119