SARS-CoV-2 requires acidic pH to infect cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry starts with membrane attachment and ends with spike (S) protein–catalyzed membrane fusion depending on two cleavage steps, namely, one usually by furin in producing cells and the second by TMPRSS2 on target cells. Endosomal cath...

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Detalles Bibliográficos
Autores principales: Kreutzberger, Alex J. B., Sanyal, Anwesha, Saminathan, Anand, Bloyet, Louis-Marie, Stumpf, Spencer, Liu, Zhuoming, Ojha, Ravi, Patjas, Markku T., Geneid, Ahmed, Scanavachi, Gustavo, Doyle, Catherine A., Somerville, Elliott, Correia, Ricardo Bango Da Cunha, Di Caprio, Giuseppe, Toppila-Salmi, Sanna, Mäkitie, Antti, Kiessling, Volker, Vapalahti, Olli, Whelan, Sean P. J., Balistreri, Giuseppe, Kirchhausen, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499588/
https://www.ncbi.nlm.nih.gov/pubmed/36048924
http://dx.doi.org/10.1073/pnas.2209514119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499588/
https://www.ncbi.nlm.nih.gov/pubmed/36048924
http://dx.doi.org/10.1073/pnas.2209514119

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