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SARS-CoV-2 requires acidic pH to infect cells
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry starts with membrane attachment and ends with spike (S) protein–catalyzed membrane fusion depending on two cleavage steps, namely, one usually by furin in producing cells and the second by TMPRSS2 on target cells. Endosomal cath...
Autores principales: | Kreutzberger, Alex J. B., Sanyal, Anwesha, Saminathan, Anand, Bloyet, Louis-Marie, Stumpf, Spencer, Liu, Zhuoming, Ojha, Ravi, Patjas, Markku T., Geneid, Ahmed, Scanavachi, Gustavo, Doyle, Catherine A., Somerville, Elliott, Correia, Ricardo Bango Da Cunha, Di Caprio, Giuseppe, Toppila-Salmi, Sanna, Mäkitie, Antti, Kiessling, Volker, Vapalahti, Olli, Whelan, Sean P. J., Balistreri, Giuseppe, Kirchhausen, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499588/ https://www.ncbi.nlm.nih.gov/pubmed/36048924 http://dx.doi.org/10.1073/pnas.2209514119 |
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