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The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy

Primary open angle glaucoma (POAG), a chronic optic neuropathy, remains the leading cause of irreversible blindness worldwide. It is driven in part by the pro-fibrotic cytokine transforming growth factor beta (TGF-β) and leads to extracellular matrix remodelling at the lamina cribrosa of the optic n...

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Detalles Bibliográficos
Autores principales: Smyth, Aoife, Callaghan, Breedge, Willoughby, Colin E., O’Brien, Colm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499597/
https://www.ncbi.nlm.nih.gov/pubmed/36142127
http://dx.doi.org/10.3390/ijms231810216