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The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy
Primary open angle glaucoma (POAG), a chronic optic neuropathy, remains the leading cause of irreversible blindness worldwide. It is driven in part by the pro-fibrotic cytokine transforming growth factor beta (TGF-β) and leads to extracellular matrix remodelling at the lamina cribrosa of the optic n...
Autores principales: | Smyth, Aoife, Callaghan, Breedge, Willoughby, Colin E., O’Brien, Colm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499597/ https://www.ncbi.nlm.nih.gov/pubmed/36142127 http://dx.doi.org/10.3390/ijms231810216 |
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