Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome

Cells respond to environmental stress by regulating gene expression at the level of both transcription and translation. The ∼50 modified ribonucleotides of the human epitranscriptome contribute to the latter, with mounting evidence that dynamic regulation of transfer RNA (tRNA) wobble modifications...

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Detalles Bibliográficos
Autores principales: Huber, Sabrina M., Begley, Ulrike, Sarkar, Anwesha, Gasperi, William, Davis, Evan T., Surampudi, Vasudha, Lee, May, Melendez, J. Andres, Dedon, Peter C., Begley, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499598/
https://www.ncbi.nlm.nih.gov/pubmed/36095201
http://dx.doi.org/10.1073/pnas.2123529119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499598/
https://www.ncbi.nlm.nih.gov/pubmed/36095201
http://dx.doi.org/10.1073/pnas.2123529119

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