Cargando…

Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome

Cells respond to environmental stress by regulating gene expression at the level of both transcription and translation. The ∼50 modified ribonucleotides of the human epitranscriptome contribute to the latter, with mounting evidence that dynamic regulation of transfer RNA (tRNA) wobble modifications...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huber, Sabrina M., Begley, Ulrike, Sarkar, Anwesha, Gasperi, William, Davis, Evan T., Surampudi, Vasudha, Lee, May, Melendez, J. Andres, Dedon, Peter C., Begley, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499598/ https://www.ncbi.nlm.nih.gov/pubmed/36095201 http://dx.doi.org/10.1073/pnas.2123529119

Ejemplares similares

The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress
por: Huber, Sabrina M., et al.
Publicado: (2019)

Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming
por: Lee, May Y., et al.
Publicado: (2019)

Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses
por: Chan, Cheryl, et al.
Publicado: (2018)

Epitranscriptomic Reprogramming Is Required to Prevent Stress and Damage from Acetaminophen
por: Evke, Sara, et al.
Publicado: (2022)

Dengue virus exploits the host tRNA epitranscriptome to promote viral replication
por: Chan, Cheryl, et al.
Publicado: (2023)

Queuine Salvaging in the Human Parasite Entamoeba histolytica
por: Sarid, Lotem, et al.
Publicado: (2022)

Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel Disease
por: Zhang, Jilei, et al.
Publicado: (2023)

Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator
por: Nagaraja, Shruti, et al.
Publicado: (2021)

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes
por: Chan, Clement T. Y., et al.
Publicado: (2015)

Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine
por: Müller, Martin, et al.
Publicado: (2015)

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
por: Chan, Clement T.Y., et al.
Publicado: (2012)

The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene
por: Leonardi, Andrea, et al.
Publicado: (2020)

tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum
por: Ng, Chee Sheng, et al.
Publicado: (2018)

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α
por: Begley, Ulrike, et al.
Publicado: (2013)

Enhanced expression of queuine tRNA-ribosyltransferase 1 (QTRT1) predicts poor prognosis in lung adenocarcinoma
por: Ma, Qianli, et al.
Publicado: (2020)

CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome
por: Jungfleisch, Jennifer, et al.
Publicado: (2022)

Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage
por: Endres, Lauren, et al.
Publicado: (2015)

Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation
por: Deng, Wenjun, et al.
Publicado: (2015)

Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor
por: Biela, Inna, et al.
Publicado: (2013)

A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
por: Chan, Clement T. Y., et al.
Publicado: (2010)

Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression
por: Gu, Chen, et al.
Publicado: (2018)

Correction: A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
por: Chan, Clement T. Y., et al.
Publicado: (2011)

Adaptor Molecules Epitranscriptome Reprograms Bacterial Pathogenicity
por: Kouvela, Adamantia, et al.
Publicado: (2021)

The Queuine Micronutrient: Charting a Course from Microbe to Man
por: Fergus, Claire, et al.
Publicado: (2015)

A System of RNA Modifications and Biased Codon Use Controls Cellular Stress Response at the Level of Translation
por: Dedon, Peter C., et al.
Publicado: (2014)

Queuine links translational control in eukaryotes to a micronutrient from bacteria
por: Müller, Martin, et al.
Publicado: (2019)

tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence
por: Chionh, Yok Hian, et al.
Publicado: (2016)

A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth
por: Rothenberg, Daniel A., et al.
Publicado: (2018)

Non-Redundant tRNA Reference Sequences for Deep Sequencing Analysis of tRNA Abundance and Epitranscriptomic RNA Modifications
por: PICHOT, Florian, et al.
Publicado: (2021)

EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis
por: Lang, Fengchao, et al.
Publicado: (2019)

Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration
por: Richard, Patricia, et al.
Publicado: (2021)

tRNA Modification Detection Using Graphene Nanopores: A Simulation Study
por: Onanuga, Khadijah, et al.
Publicado: (2017)

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast
por: Pollo-Oliveira, Leticia, et al.
Publicado: (2020)

Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells
por: Hayes, Patti, et al.
Publicado: (2020)

Correction: Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration
Publicado: (2021)

tModBase: deciphering the landscape of tRNA modifications and their dynamic changes from epitranscriptome data
por: Lei, Hao-Tian, et al.
Publicado: (2022)

Cracking the epitranscriptome
por: Schwartz, Schraga
Publicado: (2016)

Translating the epitranscriptome
por: Hoernes, Thomas Philipp, et al.
Publicado: (2016)

Epitranscriptomics of cancer
por: Tusup, Marina, et al.
Publicado: (2018)

Strategies to Avoid Artifacts in Mass Spectrometry‐Based Epitranscriptome Analyses
por: Kaiser, Steffen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gotjp20oqt5eo68k8g6q5nejnu