Common and Rare PCSK9 Variants Associated with Low-Density Lipoprotein Cholesterol Levels and the Risk of Diabetes Mellitus: A Mendelian Randomization Study

PCSK9 is a candidate locus for low-density lipoprotein cholesterol (LDL-C) levels. The cause–effect relationship between LDL-C levels and diabetes mellitus (DM) has been suggested to be mechanism-specific. To identify the role of PCSK9 and genome-wide association study (GWAS)-significant variants in...

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Detalles Bibliográficos
Autores principales: Hsu, Lung-An, Teng, Ming-Sheng, Wu, Semon, Chou, Hsin-Hua, Ko, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499600/
https://www.ncbi.nlm.nih.gov/pubmed/36142332
http://dx.doi.org/10.3390/ijms231810418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499600/
https://www.ncbi.nlm.nih.gov/pubmed/36142332
http://dx.doi.org/10.3390/ijms231810418

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