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Senescence-Independent Anti-Inflammatory Activity of the Senolytic Drugs Dasatinib, Navitoclax, and Venetoclax in Zebrafish Models of Chronic Inflammation

Telomere shortening is the main molecular mechanism of aging, but not the only one. The adaptive immune system also ages, and older organisms tend to develop a chronic pro-inflammatory status with low-grade inflammation characterized by chronic activation of the innate immune system, called inflamma...

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Detalles Bibliográficos
Autores principales: Hernández-Silva, David, Cantón-Sandoval, Joaquín, Martínez-Navarro, Francisco Juan, Pérez-Sánchez, Horacio, de Oliveira, Sofia, Mulero, Victoriano, Alcaraz-Pérez, Francisca, Cayuela, María Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499634/
https://www.ncbi.nlm.nih.gov/pubmed/36142384
http://dx.doi.org/10.3390/ijms231810468