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HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid

High-temperature requirement A1 (HtrA1) has been identified as a disease-susceptibility gene for age-related macular degeneration (AMD) including polypoidal choroidal neovasculopathy (PCV). We characterized the underlying phenotypic changes of transgenic (Tg) mice expressing ubiquitous CAG promoter...

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Detalles Bibliográficos
Autores principales: Ahamed, Waseem, Yu, Richard Ming Chuan, Pan, Yang, Iwata, Takeshi, Barathi, Veluchamy Amutha, Wey, Yeo Sia, Tun, Sai Bo Bo, Qiu, Beiying, Tan, Alison, Wang, Xiaomeng, Cheung, Chui Ming Gemmy, Wong, Tien Yin, Yanagi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499640/
https://www.ncbi.nlm.nih.gov/pubmed/36142120
http://dx.doi.org/10.3390/ijms231810206