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Sex-Dependent Effects of Piromelatine Treatment on Sleep-Wake Cycle and Sleep Structure of Prenatally Stressed Rats

Prenatal stress (PNS) impairs the circadian rhythm of the sleep/wake cycle. The melatonin (MT) analogue Piromelatine (Pir) was designed for the treatment of insomnia. The present study aimed to explore effects of Pir on circadian rhythmicity, motor activity, and sleep structure in male and female ra...

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Detalles Bibliográficos
Autores principales: Tchekalarova, Jana, Kortenska, Lidia, Marinov, Pencho, Ivanova, Natasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499655/
https://www.ncbi.nlm.nih.gov/pubmed/36142262
http://dx.doi.org/10.3390/ijms231810349