The Comparative Experimental Study of Sodium and Magnesium Dichloroacetate Effects on Pediatric PBT24 and SF8628 Cell Glioblastoma Tumors Using a Chicken Embryo Chorioallantoic Membrane Model and on Cells In Vitro

In this study, pyruvate dehydrogenase kinase-1 inhibition with dichloroacetate (DCA) was explored as an alternative cancer therapy. The study’s aim was to compare the effectiveness of NaDCA and MgDCA on pediatric glioblastoma PBT24 and SF8628 tumors and cells. The treatment effects were evaluated on...

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Detalles Bibliográficos
Autores principales: Damanskienė, Eligija, Balnytė, Ingrida, Valančiūtė, Angelija, Lesauskaitė, Vaiva, Alonso, Marta Marija, Stakišaitis, Donatas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499689/
https://www.ncbi.nlm.nih.gov/pubmed/36142368
http://dx.doi.org/10.3390/ijms231810455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499689/
https://www.ncbi.nlm.nih.gov/pubmed/36142368
http://dx.doi.org/10.3390/ijms231810455

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