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SH005S7 Overcomes Primary and Acquired Resistance of Non-Small Cell Lung Cancer by Combined MET/EGFR/HER3 Inhibition

In this study, we have examined the anticancer effects of SH005S7 on MET-amplified and (HCC827GR) NSCLC cells and their primary HCC827 cells. In vitro, first of all, cell viability and colony formation assay confirmed the growth inhibitory effects of SH005S7 on both cells. Second, SH005S7 inactivate...

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Detalles Bibliográficos
Autores principales: Kang, Sooyeon, Kim, Ji Hye, Hong, Jisoo, Moon, Ji Hong, Kwon, Yun Young, Ko, Seong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499774/
https://www.ncbi.nlm.nih.gov/pubmed/36158893
http://dx.doi.org/10.1155/2022/1840541