The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3

BACKGROUND: Evaluate the effect of the miRNA-106a/20b on the efficacy of DCs pulsed with GSCs in activating GSC-specific T cell responses. METHODS: We cultured GSCs and prepared GSC antigen lysates by apoptosis. Then, immature DCs were pulsed with GSC antigen lysates in vitro. STAT3 levels in DCs we...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Sun, Chengmei, Li, Cong, Hua, Shiting, Li, Feng, Li, Ruichun, Cai, Dongpeng, Zou, Yuxi, Cai, Yingqian, Jiang, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499788/
https://www.ncbi.nlm.nih.gov/pubmed/36157880
http://dx.doi.org/10.1155/2022/9721028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499788/
https://www.ncbi.nlm.nih.gov/pubmed/36157880
http://dx.doi.org/10.1155/2022/9721028

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