Acetylation of Atp5f1c Mediates Cardiomyocyte Senescence via Metabolic Dysfunction in Radiation-Induced Heart Damage

OBJECTIVE: Ionizing radiation (IR) causes cardiac senescence, which eventually manifests as radiation-induced heart damage (RIHD). This study is aimed at exploring the mechanisms underlying IR-induced senescence using acetylation proteomics. METHODS: Irradiated mouse hearts and H9C2 cells were harve...

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Detalles Bibliográficos
Autores principales: Zeng, Zhimin, Xu, Peng, He, Yanqing, Yi, Yali, Liu, Zhicheng, Cai, Jing, Huang, Long, Liu, Anwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499811/
https://www.ncbi.nlm.nih.gov/pubmed/36160705
http://dx.doi.org/10.1155/2022/4155565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499811/
https://www.ncbi.nlm.nih.gov/pubmed/36160705
http://dx.doi.org/10.1155/2022/4155565

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