A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells

MR1 is a highly conserved microbial immune-detection system in mammals. It captures vitamin B–related metabolite antigens from diverse microbes and presents them at the cell surface to stimulate MR1-restricted lymphocytes including mucosal-associated invariant T (MAIT) cells. MR1 presentation and MA...

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Detalles Bibliográficos
Autores principales: Lim, Hui Jing, Wubben, Jacinta M., Garcia, Cristian Pinero, Cruz-Gomez, Sebastian, Deng, Jieru, Mak, Jeffrey Y.W., Hachani, Abderrahman, Anderson, Regan J., Painter, Gavin F., Goyette, Jesse, Amarasinghe, Shanika L., Ritchie, Matthew E., Roquilly, Antoine, Fairlie, David P., Gaus, Katharina, Rossjohn, Jamie, Villadangos, Jose A., McWilliam, Hamish E.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499830/
https://www.ncbi.nlm.nih.gov/pubmed/36129434
http://dx.doi.org/10.1083/jcb.202110125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499830/
https://www.ncbi.nlm.nih.gov/pubmed/36129434
http://dx.doi.org/10.1083/jcb.202110125

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