Genetic risk factors have a substantial impact on healthy life years

The impact of genetic variation on overall disease burden has not been comprehensively evaluated. We introduce an approach to estimate the effect of genetic risk factors on disability-adjusted life years (DALYs; ‘lost healthy life years’). We use genetic information from 735,748 individuals and cons...

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Detalles Bibliográficos
Autores principales: Jukarainen, Sakari, Kiiskinen, Tuomo, Kuitunen, Sara, Havulinna, Aki S., Karjalainen, Juha, Cordioli, Mattia, Rämö, Joel T., Mars, Nina, Samocha, Kaitlin E., Ollila, Hanna M., Pirinen, Matti, Ganna, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499866/
https://www.ncbi.nlm.nih.gov/pubmed/36097220
http://dx.doi.org/10.1038/s41591-022-01957-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499866/
https://www.ncbi.nlm.nih.gov/pubmed/36097220
http://dx.doi.org/10.1038/s41591-022-01957-2

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