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Facile detection of mechanical forces across proteins in cells with STReTCh

Numerous proteins experience and respond to mechanical forces as an integral part of their cellular functions, but measuring these forces remains a practical challenge. Here, we present a compact, 11-kDa molecular tension sensor termed STReTCh (sensing tension by reactive tag characterization). Unli...

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Detalles Bibliográficos
Autores principales: Zhong, Brian L., Vachharajani, Vipul T., Dunn, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499875/
https://www.ncbi.nlm.nih.gov/pubmed/36160040
http://dx.doi.org/10.1016/j.crmeth.2022.100278