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Soluble PD-L1 in blood correlates positively with neutrophil and negatively with lymphocyte mRNA markers and implies adverse sepsis outcome

Sepsis causes a myriad of immunological reactions that result in life-threatening alterations in the human body. Immunosuppression in sepsis is partly attributed to the programmed death receptor (PD-1) and its associated ligand (PD-L1) via the regulation of lymphocytes and neutrophils. Although the...

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Detalles Bibliográficos
Autores principales: Derigs, Marcus, Heers, Hendrik, Lingelbach, Susanne, Hofmann, Rainer, Hänze, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499885/
https://www.ncbi.nlm.nih.gov/pubmed/35732880
http://dx.doi.org/10.1007/s12026-022-09302-y