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Recent progress in drug development for fibrodysplasia ossificans progressiva

Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disease caused by heterozygous missense mutations in Activin A receptor type I which is also known as Activin-like kinase 2 (ALK2), a type I receptor of Bone Morphogenetic Proteins(BMP). Patients with FOP usually undergo episodic flare-up...

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Detalles Bibliográficos
Autores principales: Meng, Xinmiao, Wang, Haotian, Hao, Jijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499916/
https://www.ncbi.nlm.nih.gov/pubmed/35536530
http://dx.doi.org/10.1007/s11010-022-04446-9