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Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions

In addition to hypoxia, inflammation is capable of inducing vascular endothelial growth factor (VEGF) expression in human retinal pigment epithelial (RPE) cells. Excessive levels of VEGF promote choroidal neovascularization and thereby contribute to the pathogenesis of wet age-related macular degene...

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Detalles Bibliográficos
Autores principales: Bhattarai, Niina, Hytti, Maria, Reinisalo, Mika, Kaarniranta, Kai, Mysore, Yashavanthi, Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499922/
https://www.ncbi.nlm.nih.gov/pubmed/35661979
http://dx.doi.org/10.1007/s12026-022-09300-0