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Injectable nanoporous microgels generate vascularized constructs and support bone regeneration in critical-sized defects

Large and aberrant bone fractures require ossification and concomitant vascularization for proper healing. Evidence indicates that osteogenesis and vessel growth are coupled in bone fractures. Although the synergistic role of endothelial cells has been recognized, vascularizing large bone grafts rem...

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Detalles Bibliográficos
Autores principales: Patrick, Matthew D., Keys, Jeremy F., Suresh Kumar, Harshini, Annamalai, Ramkumar T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499928/
https://www.ncbi.nlm.nih.gov/pubmed/36138042
http://dx.doi.org/10.1038/s41598-022-19968-x