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Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer

A common stage of advanced prostate cancer is castration-resistant prostate cancer (CRPC), greater understanding of which is required in order to address and solve the clinically difficult challenge. Cathepsin K (CTSK) is a cysteine protease that usually has a strong activity of degrading extracellu...

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Detalles Bibliográficos
Autores principales: Wu, Ning, Wang, YouZhi, Wang, KeKe, Zhong, BoQiang, Liao, YiHao, Liang, JiaMing, Jiang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499936/
https://www.ncbi.nlm.nih.gov/pubmed/36138018
http://dx.doi.org/10.1038/s41419-022-05215-8