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A machine learning-based SNP-set analysis approach for identifying disease-associated susceptibility loci

Identifying disease-associated susceptibility loci is one of the most pressing and crucial challenges in modeling complex diseases. Existing approaches to biomarker discovery are subject to several limitations including underpowered detection, neglect for variant interactions, and restrictive depend...

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Detalles Bibliográficos
Autores principales: Silva, Princess P., Gaudillo, Joverlyn D., Vilela, Julianne A., Roxas-Villanueva, Ranzivelle Marianne L., Tiangco, Beatrice J., Domingo, Mario R., Albia, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499949/
https://www.ncbi.nlm.nih.gov/pubmed/36138111
http://dx.doi.org/10.1038/s41598-022-19708-1