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A machine learning-based SNP-set analysis approach for identifying disease-associated susceptibility loci
Identifying disease-associated susceptibility loci is one of the most pressing and crucial challenges in modeling complex diseases. Existing approaches to biomarker discovery are subject to several limitations including underpowered detection, neglect for variant interactions, and restrictive depend...
Autores principales: | Silva, Princess P., Gaudillo, Joverlyn D., Vilela, Julianne A., Roxas-Villanueva, Ranzivelle Marianne L., Tiangco, Beatrice J., Domingo, Mario R., Albia, Jason R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499949/ https://www.ncbi.nlm.nih.gov/pubmed/36138111 http://dx.doi.org/10.1038/s41598-022-19708-1 |
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